dna5.hpp

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// -----------------------------------------------------------------------------------------------------
// Copyright (c) 2006-2020, Knut Reinert & Freie Universität Berlin
// Copyright (c) 2016-2020, Knut Reinert & MPI für molekulare Genetik
// This file may be used, modified and/or redistributed under the terms of the 3-clause BSD-License
// shipped with this file and also available at: https://github.com/seqan/seqan3/blob/master/LICENSE.md
// -----------------------------------------------------------------------------------------------------
 
#pragma once
 
#include <vector>
 
#include <seqan3/alphabet/nucleotide/nucleotide_base.hpp>
#include <seqan3/utility/char_operations/transform.hpp>
 
// ------------------------------------------------------------------
// dna5
// ------------------------------------------------------------------
 
namespace seqan3
{
 
class rna5;
 
class dna5 : public nucleotide_base<dna5, 5>
{
private:
    using base_t = nucleotide_base<dna5, 5>;
 
    friend base_t;
    friend base_t::base_t;
    friend rna5;
 
public:
    constexpr dna5()                          noexcept = default; 
    constexpr dna5(dna5 const &)              noexcept = default; 
    constexpr dna5(dna5 &&)                   noexcept = default; 
    constexpr dna5 & operator=(dna5 const &)  noexcept = default; 
    constexpr dna5 & operator=(dna5 &&)       noexcept = default; 
    ~dna5()                                   noexcept = default; 
 
    using base_t::base_t;
 
    template <std::same_as<rna5> t>    // Accept incomplete type
    constexpr dna5(t const & r) noexcept
    {
        assign_rank(r.to_rank());
    }
 
private:
    static constexpr char_type rank_to_char_table[alphabet_size]
    {
        'A',
        'C',
        'G',
        'N',
        'T'
    };
 
    static constexpr std::array<rank_type, 256> char_to_rank_table
    {
        [] () constexpr
        {
            std::array<rank_type, 256> ret{};
 
            // initialize with UNKNOWN (std::array::fill unfortunately not constexpr)
            for (auto & c : ret)
                c = 3; // == 'N'
 
            // reverse mapping for characters and their lowercase
            for (size_t rnk = 0u; rnk < alphabet_size; ++rnk)
            {
                ret[rank_to_char_table[rnk]] = rnk;
                ret[to_lower(rank_to_char_table[rnk])] = rnk;
            }
 
            // set U equal to T
            ret['U'] = ret['T']; ret['u'] = ret['t'];
 
            // iupac characters are implicitly "UNKNOWN"
            return ret;
        }()
    };
 
    static const std::array<dna5, alphabet_size> complement_table;
 
    static constexpr char_type rank_to_char(rank_type const rank)
    {
        return rank_to_char_table[rank];
    }
 
    static constexpr rank_type char_to_rank(char_type const chr)
    {
        using index_t = std::make_unsigned_t<char_type>;
        return char_to_rank_table[static_cast<index_t>(chr)];
    }
};
 
// ------------------------------------------------------------------
// containers
// ------------------------------------------------------------------
 
using dna5_vector = std::vector<dna5>;
 
// ------------------------------------------------------------------
// literals
// ------------------------------------------------------------------
 
constexpr dna5 operator""_dna5(char const c) noexcept
{
    return dna5{}.assign_char(c);
}
 
inline dna5_vector operator""_dna5(char const * s, std::size_t n)
{
    dna5_vector r;
    r.resize(n);
 
    for (size_t i = 0; i < n; ++i)
        r[i].assign_char(s[i]);
 
    return r;
}
 
// ------------------------------------------------------------------
// dna5 (deferred definition)
// ------------------------------------------------------------------
 
constexpr std::array<dna5, dna5::alphabet_size> dna5::complement_table
{
    'T'_dna5,    // complement of 'A'_dna5
    'G'_dna5,    // complement of 'C'_dna5
    'C'_dna5,    // complement of 'G'_dna5
    'N'_dna5,    // complement of 'N'_dna5
    'A'_dna5     // complement of 'T'_dna5
};
 
} // namespace seqan3